This 28-answer worksheet is designed to accompany Episode 1, Standing Up in the Milky Way, of the documentary television series Cosmos: A Spacetime Odyssey hosted by Neil deGrasse Tyson and follows up Cosmos: A Personal Voyage presented by Carl Sagan. Famed astrophysicist Neil deGrasse Tyson takes a tour of the Solar System and the known universe establishing the components of Earth's "address" within the Virgo Supercluster. He then shares the story of the person who championed an expansive understanding of Earth's place in the universe by presenting Renaissance Italian Giordano Bruno's vision of the universe as a limitless expanse of space and time. He then makes an exploration into the Cosmic Calendar, which dates back to the dawn of the Big Bang (similar to the presentation from episode 1 of the original series). The episode ends with deGrasse Tyson narrating how he met his mentor Carl Sagan, who hosted the first Cosmos series. Key vocabulary includes cosmos, moon, sun, Mercury, Venus, Mars, asteroids, Jupiter, Saturn, Neptune, Uranus, Voyager, Oort Cloud, rogue planet, galaxy, Local Group, supercluster, universe, history, multiverse, Copernicus, Lucretius, Bruno, Big Bang, evidence, gravity, supernova, and life. Applies to science, Earth science, astronomy, space, history, and physics.