This high school biology resource is a great addition to a natural selection unit when illustrating antibiotic resistance in bacteria. The lab uses three colors of Jellybeans to represent a species of Streptococcus with genetic variation. Within the bacterial population are least resistant, resistant, and extremely resistant bacteria. Students roll the dice to determine their course of action during an infection. Over the course of the antibiotic, the least resistant are "killed" off and the extremely resistant increase in frequency. The data are easy to graph with colored pencils and the analysis questions are easy to discuss. This fun and easy simulation takes about thirty minutes and allows students to snack on the leftover Jellybeans.