In this activity, students are provided with a wild string of DNA for a particular phenotype (There are 10 different phenotypes). They are then pick up a mutation (provided) for each of their phenotypes and transcribe and translate each DNA sequence. Once the students have determined the amino acid sequence, they are to compare their amino acid sequence to a table of amino acid sequences that correspond to various proteins.
Once they match up their phenotypes, the students are to sketch out their mutant. Every student should have a different mutant as there are 10 different phenotypes that can have an error.
This is an excellent activity to assess students' understanding on mutations.
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