What does it mean that we have different blood types? Why can a person with O- blood donate to a person with AB+ blood, but a person with AB+ blood can't donate to a person with O- blood? In my 5 years of teaching, these have been some of the harder questions to answer. Over my career, I have worked hard to create a blood typing lesson for my students that is cohesive and easy to understand. I have recorded myself teaching that lesson (see preview for one small bit - that "pumping" noise and paper moving noise you hear in the background is NOT present in the actual video - mommy/teacher problems lol). You can show this video to your students or mirror-teach and use my same strategy as you teach. You and your students will come out with extreme confidence to answer the questions, "Why do we have different blood types?", "Who can donate to who?", and "Who can receive from who?" Make sure you also download the Red Cross Blood Typing app for some extra practice with your students after the lesson!