BE AWARE THIS ACTIVITY IS INCLUDED IN THE BUNDLE FOR THE LESSON ON NUCLEIC ACIDS AND PROTEIN SYNTHESIS. This is an activity that can be modified for middle school science classes or High School Biology classes. Students will use different candies to make the nucleotides of the DNA molecule and build the two chains to make the ladder of the DNA. The third part is to demonstrate how replication is accomplished with the addition of free nucleotides to each chain. The student should learn the concept of how replication occurs during Interphase of cell division. Middle school students can learn the basics of the concept but for High School students, I make it more fast pace. Students are at lab stations and the students should have a key to their model that matches the construction of their nucleotide. I give the students an oral questioning of the structure and process of replication. This includes discussing the lead and lag strands and Okazaki fragments. I have included notes for the instructor on the questions that I ask to the student group as I go from station to station. Depending on the size of the class, the activity can be done from 45 minutes to 70 minutes in larger classes. Time can be cut by teacher pre-prepping the candy.