The “Cut-up Paragraph” strategy is a quick, highly effective learning tool. It develops long-term conceptual understanding of a topic by requiring students to read critically and interpret information rather than simply skimming through textual information. Students are given a paragraph with important information that has been cut apart into individual sentences. They then must read and interpret the sentence cards and use them to build the paragraph. In this particular Cut-up Paragraph activity, the paragraph outlines the effects of cell cycle disruption and the relationship those disruptions have to cancer. I like to give a quick pre-assessment (either written or oral) to determine what my students know about the cause of cancer before I do this activity. It is amazing what they can learn about cancer in a relatively short period of time by reading each sentence critically and interpreting how it fits with the big picture of cell cycle disruption. By the end of the activity, almost every student in my class can give me a relatively detailed explanation of what causes cancer. The great thing is, I did no direct teaching; the student does all of the learning, thinking, interpreting, and work.