Chromosomes and Genetics Worksheet Activity MS-LS3-2 HS-LS3-3

Grade Levels
6th - 8th
Formats Included
  • PDF
2 pages
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Engaging and effective middle school NGSS heredity activity!

In this activity, students will:

  • Examine alleles on chromosomes to determine genotype and phenotype
  • Draw one child to demonstrate understanding of phenotype
  • Use the Claims/Evidence/Reasoning format to predict the chromosomes of parents based on the alleles of their children
  • Answer an "extended thinking" question that requires students to think a little deeper about chromosomes and heredity

The format of this worksheet is designed to mirror the way these types of questions have been asked on standardized tests in the past. Overall, this worksheet is a great review of dominant/recessive, genotype/phenotype, and chromosomes.

Teacher Notes:

  • Please note that this resource is not editable.
  • You may find our Genetics Test useful.

Find more middle school genetics resources in the Heredity Section of our store.

Pedigree Worksheet

Rosalind Franklin Article & Questions (great sub plan)

Genetic Engineering Article & Questions

Genetics Review Worksheet

Blood Type and Codominance Worksheet

Sex-Linked Traits Worksheet

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Total Pages
2 pages
Answer Key
Teaching Duration
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to see state-specific standards (only available in the US).
Apply concepts of statistics and probability to explain the variation and distribution of expressed traits in a population. Emphasis is on the use of mathematics to describe the probability of traits as it relates to genetic and environmental factors in the expression of traits. Assessment does not include Hardy-Weinberg calculations.
Ask questions to clarify relationships about the role of DNA and chromosomes in coding the instructions for characteristic traits passed from parents to offspring. Assessment does not include the phases of meiosis or the biochemical mechanism of specific steps in the process.
Develop and use a model to describe why structural changes to genes (mutations) located on chromosomes may affect proteins and may result in harmful, beneficial, or neutral effects to the structure and function of the organism. Emphasis is on conceptual understanding that changes in genetic material may result in making different proteins. Assessment does not include specific changes at the molecular level, mechanisms for protein synthesis, or specific types of mutations.
Develop and use a model to describe why asexual reproduction results in offspring with identical genetic information and sexual reproduction results in offspring with genetic variation. Emphasis is on using models such as Punnett squares, diagrams, and simulations to describe the cause and effect relationship of gene transmission from parent(s) to offspring and resulting genetic variation.


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