For years I've maintained a simple grid grade book, but often had trouble writing the wrong grade in a block because my eyes got dizzy from the black and white stripes. To help mitigate this (and to make it look fun!), I created a colored stripe grade book. The main column on the left is different for each class so I can tell them apart, as well as by using the title. Then each assignment column is different to help separate one assignment from another. It's a simple idea, but has made recording my grades much easier.
I've include MS Word copies so you can type in information and/or make changes as you see fit, as well as a pdf copy in case that works better for you. Each single page grade sheet holds up to 24 students as that's the legal limit for science classes in NH. :)
Enjoy these little colorful beauties!