DNA Crime Lab! Can you solve the case?

Grade Levels
7th - 10th
Formats Included
  • Zip
16 pages
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Each group is given a long paper strip of DNA, a 3-page story of the missing necklace and directions on how to fingerprint and sequence their DNA. Scissors act as the restriction enzyme, cutting the DNA between every GGCC into varied length segments. As the segments are pasted into the corresponding rows on the sequencing board (imitating gel electrophoresis), the DNA fingerprint of each suspect will emerge. So, who stole the necklace? Be a crime stopper!

With a focus on literacy and collaboration, this activity teaches students about the importance of enzymes, DNA sequencing, fingerprinting, mutations that can happen if we smoke and even what it means to be a twin.

Zip file includes:

Original "Who stole the necklace?" story

Directions to solve the crime

Teacher set up/lesson plan

DNA strips

DNA pasting chart

Follow up questions

Answer keys

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Total Pages
16 pages
Answer Key
Teaching Duration
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