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DNA Replication Simulation using Pipe Cleaners
DNA Replication Simulation using Pipe Cleaners
DNA Replication Simulation using Pipe Cleaners
DNA Replication Simulation using Pipe Cleaners
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What others say

"My students enjoyed this hands-on activity for our DNA unit. It really helped them visualize DNA replication as a semi-conservative process. "
star
Alexis T.

Description

This simple activity can be done with partners or alone. The end product (shown in photo) is like catching DNA in the act of replication when it is half done. It works well when you have only one hour to do an activity and does not need the details you would need with other DNA building activities. I have used this as an introduction to replication in my life science classes.
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DNA Replication Simulation using Pipe Cleaners

Biology Buff
1.1k Followers
$2.00

Highlights

Digital downloads
Grades icon
Grades
7th - 12th
Pages
2
Teaching Duration
55 minutes

What others say

"My students enjoyed this hands-on activity for our DNA unit. It really helped them visualize DNA replication as a semi-conservative process. "
star
Alexis T.

Description

This simple activity can be done with partners or alone. The end product (shown in photo) is like catching DNA in the act of replication when it is half done. It works well when you have only one hour to do an activity and does not need the details you would need with other DNA building activities. I have used this as an introduction to replication in my life science classes.
Report this resource to TPT
Reported resources will be reviewed by our team. Report this resource to let us know if this resource violates TPT's content guidelines.

Reviews

5.0
Rated 4.95 out of 5, based on 20 reviews
20
ratings
5
18
4
2
3
0
2
0
1
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All verified TPT purchases
Great Resource
Rated 5 out of 5
September 23, 2025
My students enjoyed this hands-on activity for our DNA unit. It really helped them visualize DNA replication as a semi-conservative process.
Alexis Trujillo
(TPT Seller)
135 reviews • Arizona
Grades taught: 10th
Biology Buff
Response from
Biology Buff
(TPT Seller)
Dec 12, 2025
Great!
Rated 5 out of 5
November 16, 2023
Simple and easy to follow. Kids enjoyed it and it was a great review for a quiz.
Alfredo B.
647 reviews
Grades taught: 9th, 10th
Student populations: Learning difficulties
Biology Buff
Response from
Biology Buff
(TPT Seller)
Nov 28, 2023
Thanks
Rated 5 out of 5
August 8, 2023
Students enjoyed working on this activity to help further along their workings!
August G.
33 reviews
Grades taught: 10th
Student populations: Learning difficulties
Biology Buff
Response from
Biology Buff
(TPT Seller)
Oct 30, 2023
Great!
Rated 5 out of 5
January 12, 2023
My students LOVED this assignment! Everyone was in engaged and on task the entire period. I had them work in pairs due to supplies. Hands on is always the way to go, especially for my students with learning disabilities.
Pamela P.
1 review
Grades taught: 9th, 10th
Student populations: Autism, Learning difficulties
Biology Buff
Response from
Biology Buff
(TPT Seller)
Jan 13, 2023
Wonderful! I’m so glad your students liked it!
Rated 4 out of 5
February 26, 2022
My kiddos loved this! Very engaging and perfect for their grade level.
Tiffany N.
838 reviews
Grades taught: 10th
Biology Buff
Response from
Biology Buff
(TPT Seller)
Mar 10, 2022
Great!
Rated 5 out of 5
December 13, 2020
This was a good hands-on activity to help my students understand the process of DNA replication. I always have a stash of beads and pipe cleaners, so it didn't break my budget either! :)
Jennifer R.
127 reviews
Grades taught: 7th
Biology Buff
Response from
Biology Buff
(TPT Seller)
Dec 31, 2020
Glad to hear!
Rated 5 out of 5
October 20, 2019
Love the hands on
Theresa Sicheri
(TPT Seller)
253 reviews
Rated 5 out of 5
May 3, 2019
Good resource.
Kristen Bentzen
(TPT Seller)
90 reviews

Questions & Answers

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