Here is a complete comprehension guide for the Anne Frank House Graphic Novel. I used as a reading in my Literature class, but we made many connections to social studies/current events/geography as well. Included are questions for chapters 1-10. Each chapter includes 6-11 questions. I gave it out one chapter at a time, but you can give the whole pack as a way to preview.
The book does a great job of combining historical facts and maps and Anne's words and combined with these questions as a jumping off point.