This eleven page learning activity provides five case scenarios with multiple questions to probe student learning involving four endocrine disorders (see learning objectives below) and one nervous disorder disrupting homeostasis in five different individuals. The student will need to do research either using the internet or other resources to assess the symptoms and test results with each patient scenario In this manner, they will be able to determine the disease or condition disrupting the homeostasis in each individual. This activity may be used in whole or in part depending upon your class or your needs. The activity is included as an editable word document as well as a pdf file. A suggested answer key for the questions and graph associated with the activities is included. The student document and answer key are enclosed in the downloadable zip file. This activity is well suited for both individual and student group work.
It is recommended that this activity will work best with advanced level Biology students.
AP Biology Learning Objectives Addressed
LO 2.15 The student can justify a claim made about the effect(s) on a biological system at the molecular, physiological or organismal level when given a scenario in which one or more components within a negative regulatory system is altered.
LO 2.16 The student is able to connect how organisms use negative feedback to maintain their internal environments.
LO 2.17 The student is able to evaluate data that show the effect(s) of changes in concentrations of key molecules on negative feedback mechanisms.
LO 2.18 The student can make predictions about how organisms use negative feedback mechanisms to maintain their internal environments.
LO 2.19 The student is able to make predictions about how positive feedback mechanisms amplify activities and processes in organisms based on scientific theories and models.
LO 2.20 The student is able to justify that positive feedback mechanisms amplify responses in organisms.
Endocrine System Student Learning Goals
Upon the completion of this activity the student will be able to:
1. discuss and describe an example of a negative feedback mechanisms in humans.
2. discuss the feedback loop which regulates the secretion of thyroid hormones.
3. list two hormones of the adrenal glands, describe their function, and explain how their secretion is controlled.
4. discuss how goiter, diabetes, Addison's disease and Grave's disease disrupt homeostasis.
NGSS Standard Addressed
LS1-2. Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms.
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