Enzymes Color by Number

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Amy Brown Science
Grade Levels
9th - 12th, Homeschool
Formats Included
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10 pages
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Amy Brown Science


This Enzymes and the Chemical Reactions of the Cell coloring activity is a fun way to cover biochemistry concepts such as enzymes, catalysts, active sites, and the lock and key hypothesis of enzyme functioning. (See complete list of concepts below.) Students will complete a set of 26 review questions. Each correct answer will lead to a code for coloring a section of the coloring page. As students progress through the questions, the picture slowly comes to life. This resource includes student worksheets, two coloring page versions, complete answer key, and a teacher guide. Students love to color!

What is included in this resource?

  • Full Size Student Coloring Page PDF - Not Editable
  • Half Size Student Coloring Page PDF - Not Editable
  • Student Questions Worksheet - Editable
  • Coloring Page Answer Key
  • Questions Worksheet Answer Key
  • Teacher Guide

What will the students be doing?

  • Students are given the two-page handout containing the enzymes review questions and the coloring page (full size or half size) you have selected. You decide which is best for your students.
  • As each question is completed, students will color the appropriate sections on the coloring page.
  • As students progress through the activity, the picture comes to life.

What concepts are covered?

This activity consists of 26 review questions on enzymes.

  • The role of chemical reactions in the cell, definitions of chemical reactions, reactants, and products.
  • Energy in reactions, the breaking and forming of chemical bonds, the absorbing and releasing of energy during biological reactions.
  • Activation energy
  • Energy Absorbing Reactions
  • Energy Releasing Reactions
  • What are Enzymes?
  • The Essential Role of Enzymes in Living Cells
  • Enzymes make reactions take place faster and at a lower temperature.
  • Enzymes lower the activation energy of a reaction.
  • Comparison of enzymes and catalysts.
  • How enzymes work, active sites, enzyme-substrate complex, new products.
  • Facts about enzymes.
  • Factors that affect the functioning of an enzyme:  Temperature and pH.
  • Denatured enzymes.

** Please note: The questions are for review and reinforcement. Students will need prior instruction in order to complete these problems. The questions are written for a first year biology class.

What materials are needed?

  • One coloring page per student
  • One 2-Page Question handout per student
  • 24-count Crayola Colored Pencils Set.
  • Students will need these 12 colors: Red, gray, pink, green, light blue, dark blue, yellow, orange, black, brown, tan, and purple.

How can this resource be used?

  • Complete as a whole classroom activity as you teach your lessons on biochemistry
  • Homework Assignment
  • Quiz on enzymes
  • Review for Unit Test
  • Substitute Teacher Folder Activity
  • End of Course Test Review

Related resources include the following:

Enzymes Complete Teaching Bundle

Enzymes Task Cards

Enzymes and Catalysts and Chemical Reactions: PowerPoint with Notes for Student and Teacher

FREE LAB - Catalase: An Enzyme Common to Both Plants and Animals

Enzymes and Catalysts Homework / Study Guide

Lab: Cells, pH and buffers

Lab: The Effect of the Enzyme Amylase on Starch

Lab: The Release of Heat in an Enzymatic Reaction

Enzymes, Catalysts and Chemical Reactions Crossword Puzzle

Enzymes and Chemical Reactions Graphing and Critical Thinking Worksheet

Enzymes and Catalysts Quiz / Test

Enzymes and Catalysts: Jeopardy Review Game

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Total Pages
10 pages
Answer Key
Teaching Duration
45 minutes
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to see state-specific standards (only available in the US).
Analyze the structure of the relationships among concepts in a text, including relationships among key terms (e.g., force, friction, reaction force, energy).


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