Summary: This activities is a hands-on inquiry based approach to helping students relate meiosis to Mendel’s laws of inheritance, hybrid crosses, and Punnett squares. It allows students to experience how meiosis is significant to sexual reproduction. It also demonstrates how and why Punnett squares are used to calculate the probable genetic outcome of offspring. It helps students better understand the meaning of genotypic and phenotypic ratios. It is a great activity to introduce a genetics unit, demonstrate Mendel’s Law of Segregation, and teaches the basics of Punnett squares.