This is a fun activity that is played in partners. It is the traditional tic-tac-toe game but students must evaluate expressions involving positive and negative exponents and scientific notation to place their X or O on the game board. Two games are included with this download and a blank game board is also included for students to make their own games to challenge one another! I often use this game as a review before a quiz and students love it and are very engaged while doing the activity. It is also a great math center activity that students can work on independently with partners.