I have bundled two versions of this genetic disorders worksheets. They both cover the same chromosomal diseases but one is short answer and the other asks the students to describe the disease symptoms.
In both sets the students are given 8 karyotypes that they need to identify by gender and figure out what chromosomal abnormalities are in each.
The students can then take that information and research it online or at a library to find the syndrome's name and symptoms (long answer set). The teacher key is included for both.
The students' worksheets are five pages long since they include an introduction in each set. The teacher keys are four pages long for each set.
You can use both sets for differentiation as well.