1. Determine if the given rational expressions have the same Least common denominators.
2. If not, find their Least common denominator.
3. Rewrite the given rational expressions as equivalent rational expressions with the same common denominator.
4. Apply the basic definition of subtracting rational numbers with a common denominator.
5. Simplify the final result by canceling out common factors in the numerator and denominator of the final result to attain the simplest form.