High School Biology Lab Experiments and Activities - Set 1

Grade Levels
7th - 11th, Homeschool
Formats Included
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  • Activity
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Easel Activities Included
Some resources in this bundle include ready-to-use interactive activities that students can complete on any device. Easel by TpT is free to use! Learn more.


Need some ideas for fun Biology labs, experiments, and activities? Never taught a high school Biology course and don't know where to start? These fun and easy labs are the perfect solution! Topics covered include: characteristics of living things, scientific method, properties of water, enzymes, cells, osmosis, cellular respiration, DNA, transcription, human genetics, and biotechnology.

Save yourself TONS of time and also save 20% instead of purchasing the labs individually!

You may also be interested in my Biology Lab Bundle: Set 2 or Animal Dissection Lab Bundle.

Each lab or activity includes teacher directions, a materials list, student procedures, discussion questions, and an answer key.

These labs are thorough, well-planned, and have been implemented many times in my own classroom. I've used these activities with both public school classes and homeschool co-op classes because they cover all of the essential biology topics and use inexpensive materials.

Labs included in this bundle:

1. Characteristics of Living Things- Students use non-living objects to investigate what characteristics are shared by all living things

2. Finding the Lighthouse Diamond- Solve a mystery using the scientific method

3. Properties of Water- Stations to illustrate the unique properties of water (ex: cohesion, adhesion)

4. Potato Enzyme Lab- Demonstrate enzymatic reactions using catalase from potatoes*

5. Diffusion & Osmosis- Use deshelled eggs to observe hypertonic and hypotonic solutions*

6. Introductory Microscope Lab- Practice microscope skills and observe cellular organelles*

7. DNA Extraction Lab- Extract visible DNA from strawberries*

8. DNA Sequencing- Make silly sentences to practice protein synthesis

9. Human Genetic Traits- Examine dominant and recessive traits within the class

10. Biotechnology Lessons- Learn about biotechnology including genetic engineering, CRISPR, and DNA fingerprinting

11. Barf Bag Lab- Observe the process of fermentation in this wonderfully gross lab*

*Update: These five labs now have a video demonstration available on my YouTube channel. They go perfectly along with the lab directions and student worksheets.

*Click on the PREVIEW of each resource to get a closer look at the resources available in this bundle.*


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Total Pages
Answer Key
Teaching Duration
1 Semester
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to see state-specific standards (only available in the US).
Construct a scientific explanation based on evidence for how environmental and genetic factors influence the growth of organisms. Examples of local environmental conditions could include availability of food, light, space, and water. Examples of genetic factors could include large breed cattle and species of grass affecting growth of organisms. Examples of evidence could include drought decreasing plant growth, fertilizer increasing plant growth, different varieties of plant seeds growing at different rates in different conditions, and fish growing larger in large ponds than they do in small ponds. Assessment does not include genetic mechanisms, gene regulation, or biochemical processes.
Plan and conduct an investigation of the properties of water and its effects on Earth materials and surface processes. Emphasis is on mechanical and chemical investigations with water and a variety of solid materials to provide the evidence for connections between the hydrologic cycle and system interactions commonly known as the rock cycle. Examples of mechanical investigations include stream transportation and deposition using a stream table, erosion using variations in soil moisture content, or frost wedging by the expansion of water as it freezes. Examples of chemical investigations include chemical weathering and recrystallization (by testing the solubility of different materials) or melt generation (by examining how water lowers the melting temperature of most solids).
Develop a model to describe how food is rearranged through chemical reactions forming new molecules that support growth and/or release energy as this matter moves through an organism. Emphasis is on describing that molecules are broken apart and put back together and that in this process, energy is released. Assessment does not include details of the chemical reactions for photosynthesis or respiration.
Construct and revise an explanation based on evidence for the cycling of matter and flow of energy in aerobic and anaerobic conditions. Emphasis is on conceptual understanding of the role of aerobic and anaerobic respiration in different environments. Assessment does not include the specific chemical processes of either aerobic or anaerobic respiration.
Apply concepts of statistics and probability to explain the variation and distribution of expressed traits in a population. Emphasis is on the use of mathematics to describe the probability of traits as it relates to genetic and environmental factors in the expression of traits. Assessment does not include Hardy-Weinberg calculations.


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