Impacts of Botox & Myasthenia Gravis at the Neuromuscular Junction- key included

Grade Levels
10th - 12th
Formats Included
  • Google Docs™
2 pages
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  1. These are my favorite resources for Anatomy & Physiology! I've taught the class since 2010, and it's been an ongoing goal to take a class that can be super heavy lecture-based and make it more interactive as often as possible. This bundle has some video guides for Crash Course videos that I use
    Price $110.00Original Price $123.00Save $13.00


If you are interested in pushing the critical thinking skills of your Anatomy & Physiology (or upper-level Biology) students a bit further, this worksheet is for you. It is designed to have students evaluate a model and apply their knowledge to understand what's happening - higher level Bloom's tasks. Students need to use what they know to determine how both Botox and MG impact the synapse between a neuron and skeletal muscle.

I use this worksheet when I teach the nervous system; my students learn about the muscular system prior to the nervous system.

Students need to have background in/an understanding of the following in order to complete this worksheet:

  • The idea that muscles shorten/contract when stimulated by a neuron (if they know the word neuromuscular junction, even better!)
  • That acetylcholine is the neurotransmitter associated with muscles
  • What the word “effector” means
  • The basic parts of a neuron- they need to recognize that they’re looking at axon terminals
  • The basics of conductivity - that neurotransmitters are released into the synapse, and when they attach to receptors, they cause an action to occur in the postsynaptic neuron or the effector  (in this case, the effector is muscle, and it is triggered to contract) 
  • The idea of an autoimmune disorder- that antibodies are part of the immune system, and in an autoimmune disorder, the antibodies mistakenly attack something in the body, creating issues.

I recommend using this as a scaffolded worksheet. I have more details included about how I use this in the actual product, but my general recommendation is to do the first part (Botox) with the class/as a discussion, and then have small groups or individuals do the second part (Myasthenia Gravis) on their own to see if they can transfer and apply their understanding to a new situation.

This is in Docs & is set up in a way that you can immediately drop it into your LMS of choice (Classroom, Schoology, etc). The answer key is provided at the end.

You can purchase this same item at a slightly lower price without the key.

Total Pages
2 pages
Answer Key
Teaching Duration
30 minutes
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to see state-specific standards (only available in the US).
Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms. Emphasis is on functions at the organism system level such as nutrient uptake, water delivery, and organism movement in response to neural stimuli. An example of an interacting system could be an artery depending on the proper function of elastic tissue and smooth muscle to regulate and deliver the proper amount of blood within the circulatory system. Assessment does not include interactions and functions at the molecular or chemical reaction level.


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