I like to use Google+ to create classroom communities where my students discuss the literature they're reading. In this forum, I post provocative questions, polls/surveys, related video, and the like.
For sale are the pre-reading questions, chapter questions, and post-reading questions that I post in my Google+ forum.
The questions are designed to provoke deep thinking, though some questions are simply comprehension. I include a range so that all students who want to answer can find a question that they feel comfortable with.
I use these questions with honors sophomores, but I feel that they would be appropriate for high school freshmen, juniors, and seniors as well.
You could also use these questions as chapter quizzes.