This square puzzle allows a fun, challenging way for students to review the 4 macromolecules (lipids, carbohydrates, nucleic acids, and proteins). Topics on the puzzle include macromolecule elements, examples, monomers, functions, structure, and food sources. The original, non-cut sheet can be used as an answer guide since they are arranged in the correct order on the sheet.
Instructions: Cut out each individual square and distribute one sheet worth of squares to each student or group doing the activity. Have students match the ends of the squares together until they get a 4 x 4 square where every side of a square matches with the side next to it.
*Students can work individually, with partners, or in small groups. I had students work in partners and made sure everyone started at the same time. The first group to finish the puzzle correctly won stickers. This gets students more motivated to participate when there is some competition involved.
*There are two sets of puzzles included in the download. One has words on the outside and one has stars on the outside. The stars make it easier to determine which pieces are on the outside, so you can differentiate the activity toward student needs.
*This activity can be used as a small part of a class period or can be utilized for a whole class period. You can do the activity once or as many times as you want for timing. You can keep having students re-do the puzzle to see who can put it together the fastest or you can mix up partners and groups to see if that changes the outcomes.
*You can edit the puzzle since it will be a word document with text boxes for the sides of the boxes. You can add any text you want into the boxes whether you want to change an example or change the topic of the puzzle completely.