Muscles aren't simply blobs of cells! When you look at the anatomy of a muscle, it is like the Russian nesting dolls - one large unit that can be broken down into smaller and smaller parts. In this lab, students can create a muscle and the subunits of a muscle out of straws, construction paper, and tape. First, students create sarcomeres... Then use the sarcomeres that they created to make a myofibril... Then use the myofibrils they created to make myocytes... Then use the myocytes they created to make fascicles. Lastly, students use the fascicles they created to make a muscle! All the while, they are wrapping each subunit in its respective epimysium, endomysium, or perimysium. My students used to hate learning the structure of a muscle. Now, with the help of this lab, they can visualize this complex anatomy and go into their test with confidence!