Let's face it, Word Search puzzles are usually busywork. They are given to substitutes, to pass the time. But, c'mon, all students have to do is search for letters. Word Search puzzles do not challenge. Until now!
Have the students answer questions or fill in the blanks to get the clues. Then they search for the words. They have to know the material.
I've used this for vocabulary words, Literary Terms, story points, and much more. Accompanying is a small word search puzzle using "Romeo & Juliet."
You can create a word search using any number of tools on the Internet. My favorite is Puzzlemaker.com.