In this lesson, we combine concepts from general biology, cell biology, microbiology, and chemistry and tie it all together to discover how anti-infectives work. In it, we discuss antibiotic selectivity, transcription/translation, reverse transcription, Gram staining, and antibiotic resistance. We also introduce multiple antibiotics and antivirals, including fluoroquinolones, macrolides, penicillin, and NNRTI/NRTIs.
At the end of the lesson, there is an activity where students must design their own antibiotic, either individually or in groups. This is a great way to tie everything they have been learning together and have them apply that knowledge to a real-world scenario!
Key words: DNA, RNA, pharmacology, pharmacy, medicine, drug, antibiotic, transcription, translation, bacteria, microbiology, ribosome, cell wall, HIV, antiviral, reverse transcriptase.