"Microcosmic God" by Theodore Sturgeon works well as an independent study assignment. I've used it with students who refused to do anything else in class because it captures the imagination. It's a decent short story to use as part of a science-fiction course, too, but it could certainly be used in a science class, too, as a way of discussing what we need to be careful of creating with science. Maybe a bit like Jurassic Park .
This download, while created for independent readers, could also be used as group work. The story is 20 pages and should be available online (I provided a link working in 2015). One day reading in class and finish as homework, and then this activity.
The activity is five questions with about 50 separate blanks to fill in, the most prevalent being vocabulary. Students are also encouraged to imagine a world where technology might have negative consequences, which would make this reading a possible companion to Brave New World or other speculative science fiction.
The story, being only 20 pages, lends itself to being used in a science class. While you might like to show Gattaca instead, your school board might not approve of the use of class time. This story can address some of the same themes. Actually, it might be a bit more like a prequel to The Terminator or The Matrix concepts, but the idea is that technological advancements can be dangerous and playing God might not result in all positives.
If you are homeschooling or in a religious school, pre-read the story. It involves evolution of a species, so it might not work with your views, but if you imagine the little critters as nanobots, it's about the same and still asks the same questions.
Take a chance on an older story with themes that are futuristic yet go further back than Shakespeare's Prospero.