This activity is a hands-on approach to modeling semiconservative DNA replication. By providing a "DNA stand" on one color of paper and free nucleotides on a second color, the student uses scissors and glue to replicate the original stand into two new strands.
In addition to the paper model, there is a worksheet that reviews basics of DNA structure (building blocks, base pair rules, instrumental scientists in the quest to discover DNA structure), and a writing prompt that asks students to reflect on the activity and the importance of the two colors of paper.
This activity is useful for any general biology class. Fully editable Word document allows you to customize for your needs. This activity can be completed within one 50 minute class period.