This lab uses a simple DNA model and applies the inquiry process to compare and contrast three types of point mutations and their resulting protein products. Students model the process of mutation through replication. It allows students to practice transcribing an mRNA codon sequence from both the original and mutated DNA strands, and translate the amino acid sequences using the genetic code, for comparison in a written analysis and conclusion. This lab usually takes a block period (90 minutes) or two 45 minute class periods. It is a great way to introduce and model point mutations, review transcription and translation, all while practicing the process of the scientific method.