This document provides higher level, thought-provoking, text-dependent comprehension questions for the book, One for the Murphys by Lynda Mullaly Hunt. (1-2 questions per chapter). These questions can be used in both a guided reading setting or as a supplement to a literature circle to get students thinking about what they are reading. A complete list of challenging vocabulary words are included in a "word/what I think it means" format to encourage students to use their context clues. Page numbers are included for each word.