Protein Folding Activity with Mutations

Protein Folding Activity with Mutations
Protein Folding Activity with Mutations
Protein Folding Activity with Mutations
Protein Folding Activity with Mutations
Protein Folding Activity with Mutations
Protein Folding Activity with Mutations
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415 KB|3 pages
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Product Description
This EDITABLE, hands-on activity asks students to explore the chemical properties of amino acids and how they determine the shape of a protein. Students place amino acids (beads) on polypeptide chain (pipe cleaners or a wire). Each color bead represents an amino acid with a different property: hydrophobic, hydrophilic, positive and negative charges.

After answering analysis questions, students add a mutation. They change one amino acid and see how it affects the structure of their protein. Finally, students apply what they learned to a real world situation: sickle cell anemia.


HS-LS1-1.Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells. [
Total Pages
3 pages
Answer Key
N/A
Teaching Duration
45 minutes
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