When I started making this, I wanted something more than a coloring page to help my students really understand protein synthesis. This particular activity would be great to cover as a class after introducing topics, OR it can be used as individual/partner practice as review for an exam. Each page covers a different part of the process:
1. Explains the central Dogma: DNA --> RNA --> Protein
2. Students use real sequenced DNA data to determine the base pairs.
3. Transcription: Identify key enzymes and transcribe the original strand into mRNA.
4: Translation: Identify codons, anticodons, tRNA, and amino acid sequence.
5: Mutations: What happens when we make a change to any part of the strand?
6: Case study: Sickle Cell Anemia - students examine a normal sequence from DNA to protein and a mutated sequence from sickle cell to protein. They need to summarize how the structure of DNA determines the structure of a protein, which determines its function.
HS-LS1-1: Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells.