This set of 10 worksheets is a re-make of worksheets I had on my site before. With more research and more understandable information, I think you will find them interesting and informative. They cover the most common psychoactive abused drugs (cocaine, amphetamines, heroin, marijuana, ecstasy, PCP, LSD, ) and also includes tobacco (nicotine), caffeine and alcohol. These worksheets can be used as students homework or can be used as a lecture aid. Students label the main organs, write how each is affected by the particular drug and write about how the synapse is affected by that drug. A colored, informative key is included for each drug along with informational pages on each drug and it's group. Detailed information about the action of neurotransmitters and drugs on the synapse is included. I have found these worksheets to be informative and interesting for high school kids, but I think they could also work for middle school.