This lesson has students examine sources of error during meiosis, then challenges them to examine karyotypes and determine what syndromes can result from unusual arrangements of chromosomes.
Your purchase includes: 1. a six page classwork sheet 2. Twelve karyotype results 3. Six more karyotypes (on two sheets of paper; students are told that these were obtained as a result of amniocentesis tests) 4. A "Medical Reference Guide" listing symptoms and life expectancy for 10 chromosomal syndromes, which is designed to be printed as a booklet to distribute to students.
In this lesson students begin by illustrating a complete model of meiosis, including independent assortment and crossing over. Students are then asked to rate their comfort with these concepts before they move on. If they are comfortable, they then draw pictures of what meiosis would look like if non-disjunction errors occurred during division 1 or division 2 of meiosis, and read about what mistakes can happen during crossing over.
Students next examine 12 different karyotypes (2 healthy and 10 from individuals with chromosomal syndromes.) NOTE: I put copies of these 12 karyotypes into file folders, and then distribute 1 file folder per table. Students will compare the karyotypes of individuals with chromosomal syndromes to the karyotypes of unaffected individuals in order to determine what is unusual. By doing this, they make themselves a "karyotype key."
Once the key is completed, I collect the file folders and then ask students to examine amniocentesis results in order to determine if 6 pregnancies are healthy. They should use both their karyotype key and their "medical reference guide" to complete this task.
1. This lesson generally takes my students a little less than 2 class periods. I encourage students who finish early to finish filling out their medical reference guide, including taking notes on anything that confuses them about mitosis or meiosis. (There is a blank back on the reference guide for this purpose.) I then allow my students to use their medical reference guide during the chapter test. =)
2. Follow these instructions in order to print the medical reference guide so that, when folded as a book, all pages are right side up and the disorders are in alphabetical order. Put odd pages right side up and even pages upside down. Make sure that your pages are back into correct sequence (1-6) before printing. Print double sided.
3. This lesson is part of a series. Companion lessons may be found below.
Introduction to mitosis: https://www.teacherspayteachers.com/Product/Addressing-Misconceptions-in-Mitosis-5136129
Introduction to meiosis: https://www.teacherspayteachers.com/Product/Addressing-Misconceptions-in-Meiosis-5148179)
Meiosis- Understanding Independent Assortment and Crossing Over (Two Lessons): https://www.teacherspayteachers.com/Product/Meiosis-Understanding-Independent-Assortment-and-Crossing-Over-5161941
To purchase the full series at a discounted price, check out this bundled product: https://www.teacherspayteachers.com/Product/Bundled-Lessons-Entire-Cell-Division-Series-5169856
Thank you, and happy teaching!