This worksheet could be used in two ways.
1) For younger students, have them fill it out using manipulatives. Starting with 2 unifix cubes (or something similar), keep adding groups of 2 until they have identified the multiples of 2. Then continue with the next column.
2) For older students, have them fill it out as a quick reference guide to have handy as they work on more complex multiplication, division, fractions problems, etc.
The arrow at the bottom signifies that, if the paper were long enough, the multiples could continue forever.