This activity can be used and adapted for many grade levels. I created it for my fourth grade science class that focuses on electricity. The rules are somewhat focused on the electrical aspects (keeping exposed wires dry, etc.), but there are some general safety rules, too.
This product includes 12 separate science rules, feel free to use what you need for your grade level! I had students complete the project in groups, and each small group had to glue their rule onto a poster they made, depicting what to do in order to follow that rule during a science lab or experiment.
I have also included a rubric that I created and used to evaluate students' poster projects.