Explore how mutations in key cell cycle regulators lead to uncontrolled cell growth and cancer in this engaging, real-world case study activity. Students analyze three cancer scenarios, thyroid carcinoma, melanoma, and leukemia, to investigate how disruptions in pathways like MAPK, CDK4/Rb, and BCR-ABL affect cellular control and therapy response. Designed for AP Biology or honors-level classes, this resource integrates molecular biology, experimental design, and bioethics, making complex cellul