Seth Rojello

OverviewThis engaging disease transmission simulation helps students model how infectious diseases spread through a population. Using a hands-on liquid-exchange activity, students investigate contact patterns, infection spread, asymptomatic transmission, and public health interventions. Students analyze class data, calculate percentages, trace possible transmission pathways, and write a Claim, Evidence, Reasoning response based on evidence.This resource is ideal for teaching epidemiology, infect

OVERVIEWThis hands-on Disease Transmission Simulation helps students model how infectious diseases spread through a population.Students exchange liquid to represent contact between individuals, test samples for a simulated infection, and use contact-tracing data to determine the most likely original infected person.This activity is perfect for teaching:• Disease transmission• Epidemiology• Contact tracing• Scientific modeling• Data analysis• Graphing• CER writingSTANDARDS ALIGNMENTNGSS Middle Sc

Explore how mutations in key cell cycle regulators lead to uncontrolled cell growth and cancer in this engaging, real-world case study activity. Students analyze three cancer scenarios, thyroid carcinoma, melanoma, and leukemia, to investigate how disruptions in pathways like MAPK, CDK4/Rb, and BCR-ABL affect cellular control and therapy response. Designed for AP Biology or honors-level classes, this resource integrates molecular biology, experimental design, and bioethics, making complex cellul

This resource provides a complete hands on lab investigation that guides students through exploring cellular respiration in yeast by measuring CO₂ production under different sugar concentrations. Students run a clear experiment, collect data, analyze respiration trends, and answer rigorous AP level questions that deepen their understanding of glycolysis, aerobic respiration, fermentation, enzyme activity, and limiting factors. This activity works for both traditional and advanced biology classro

This engaging chromatography lab introduces students to plant pigments and molecular separation techniques. Students extract pigments from spinach leaves, run a chromatography strip, calculate Rf values, and analyze pigment polarity, solubility, and function in photosynthesis. The resource includes everything needed for a complete lesson including teacher instructions, safety notes, a student lab sheet, analysis questions, application tasks, and a data table. This activity is ideal for deepening

Bring the cell membrane to life with this interactive Cell Membrane Foldable Activity! Perfect for middle and high school biology, this hands-on model helps students visualize and understand the fluid mosaic model, selective permeability, and membrane transport mechanisms. Students will construct a detailed foldable that illustrates the phospholipid bilayer, membrane proteins, cholesterol, and various transport types while reinforcing their understanding of homeostasis and cellular communic

This hands-on lab investigation introduces students to Brownian motion as observable evidence of molecular activity. Using a microscope, students analyze how temperature affects particle movement and relate their findings to diffusion, osmosis, and homeostasis within cells. Designed for high school and AP Biology, this engaging lab reinforces the kinetic molecular theory and connects microscopic motion to macroscopic biological processes. Standards Alignment: NGSS (High School): HS-LS1-3: Provid

This hands-on lab engages students in exploring the process of osmosis and water potential (Ψ) using de-shelled chicken eggs as model cells. By comparing changes in egg mass and volume in distilled water and corn syrup, students gain a clear understanding of tonicity, solute potential (Ψs), and cellular homeostasis. The activity reinforces key concepts in cell transport and helps students connect microscopic processes to real-world examples such as IV fluids, dehydration, and plant water balance

This hands-on lab engages students in exploring how environmental conditions affect enzyme activity using catalase extracted from potato tissue. Students will test the effects of temperature, pH, and substrate concentration on enzyme performance, collect data, calculate reaction rates, and graph results to analyze enzyme kinetics. Perfect for reinforcing concepts of protein structure, enzyme-substrate interactions, and metabolic regulation, this activity brings abstract biochemical principles

This engaging activity introduces students to the critical role of buffers in maintaining homeostasis. Using butterfly pea flower tea as a natural pH indicator, citric acid as an acid source, and baking soda solution as a buffer, students investigate how biological systems resist drastic pH changes. Students will record data, construct graphs, and connect their results to real-world biological systems such as blood pH regulation, lactic acid buildup during exercise, and ocean acidification. Stan

This engaging lab activity introduces students to capillary action, the process that moves water through narrow spaces without external forces. Using simple household and classroom materials, students observe water movement in paper towels and celery stalks, collect and analyze quantitative data, and connect their findings to plant physiology, ecology, and real-world applications in medicine, engineering, and technology. Designed for AP Biology but adaptable to high school biology, this resour

Engage your biology or AP Biology students with this hands-on, inquiry-based activity where they analyze real food samples to uncover the macromolecules present. Students perform biochemical tests (Benedict’s, Iodine, Biuret, and Brown Paper), draw molecular structures, and use experimental reasoning to solve a food-based mystery. This engaging resource strengthens lab skills, reinforces biochemistry content, and connects molecular biology to real-world nutrition. Standards Alignment:This resour

Challenge your students to think beyond memorization with this rigorous and engaging biology activity that redefines what it means to be alive. Perfect for high school or honors biology, this resource combines molecular biology, cell theory, biochemistry, and evolutionary theory to help students apply scientific reasoning to real-world and theoretical examples like viruses, fire, robots, and synthetic cells. Standards Alignment: NGSS HS-LS1-1: Structure and Function NGSS HS-LS1-2: Systems of Spe

Overview: Explore how natural disasters reshape ecosystems with this in-depth, NGSS-aligned resource on disturbance ecology. Designed to develop systems thinking, this multi-part lesson guides students through case studies, ecological modeling, and evidence-based argument writing. Students will analyze the cascading effects of wildfires, floods, hurricanes, droughts, and volcanic eruptions on biodiversity, nutrient cycling, succession, and evolutionary adaptation—perfect for high school and adva

This engaging and standards-aligned AP Biology resource dives deep into the science of biodiversity and how we quantify it. Students explore and compare four major biodiversity indices—Simpson’s Diversity Index, Shannon-Weiner Index, Species Richness, and Pielou’s Evenness—through scaffolded explanations, real-world data scenarios, and critical thinking prompts. It’s perfect for introducing ecological data analysis or enhancing your biodiversity or ecosystem unit. Standards Alignment: NGSS (High

This advanced biology activity challenges students to calculate, analyze, and interpret biodiversity using Simpson’s Index (D), Shannon-Weiner Index (H'), and Pielou’s Evenness (J). Through real-world datasets, students explore species dominance, ecological resilience, evolutionary pressures, and the impact of human disturbances on biodiversity. This resource builds data analysis, ecological reasoning, and graphing skills aligned with AP Biology expectations. Standards Alignment: NGSS for Mid